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Risser, D

Disc degeneration and cellular senescence reduce stem cell marker expression (CD90, CD73, TIE2, CD24) and impair spheroid colony-forming unit (CFU-S) capacity in NPPCs, accelerating cellular depletion [69]

doi: 10.1172/jci.insight.158193 525 SpolskiRLeonardWJ
This can lead to a more even, "glowing" appearance rather than a dramatic change in base skin color
