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Description
The ORF of F0726_RS04210 encoades a 453 amino acid glutathione disulfide reductase with a theoretical isoelectric point of 6.58 and molecular mass of 49.2 kDa

Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay

It improved motor function in rats

The set of candidate SNPs that yield high radioresistance could be identified, making the use of targeted gene editing technologies (e.g., CRISPR/Cas9) to replicate those SNP variants in individual humans possible (181, 182)
