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Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

The FEBS Journal

While agonist peptides based on either scaffold are potent in rat obesity models 2,10,11,12,13 , only a transient weight loss effect is observed with sCT in mouse diet-induced obesity (DIO) models 14 , indicating that there may be distinctions in the mode of action of individual dual agonists

developed a glomerulus-on-a-chip (GOAC) by reconstructing the glomerular filtration barrier on a microfluidic chip using human podocytes and glomerular endothelial cells (hGEC)