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The issue is, and the reason why weve probably been talking about it so much in the past five years is certain triggers can continuously activate those mast cells, and if your mast cells are constantly being activated, or what we know is the syndrome of Mast Cell Activation Syndrome, youre constantly releasing those mediators

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Targeted specificity was confirmed, as EphA2-negative cells showed no significant changes in EGFR expression or chemosensitivity
