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#Pharmacology #NSAIDs #ClinicalPharmacy #PharmaceuticalScience #DrugMechanism #PharmacyStudents #MedicalEducation To view or add a comment, sign in Medical Alert: A Dangerous Drug Combination That Could Trigger Seizures A new study has found that combining Tramadol, a commonly prescribed painkiller, with certain antidepressants (such as Fluoxetine, Paroxetine, Sertraline, and Bupropion) can significantly increase the risk of seizures, especially in older adults

Animal studies have failed to establish a lethal dose even at concentrations thousands of times above therapeutic levels

FDA Regulatory Framework The FDAs position centers on two realities: (1) BPC-157 is not an approved drug, and (2) FDA has raised safety concerns related to compounding it from bulk substance