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Under normal conditions, this axis helps regulate functions such as digestion, immunity, and mood (Powell et al., 2017

The presence of copper ions may disrupt this process, resulting in the inability of the P53 protein to function correctly

Trends Biochem Sci 39:199218 Hayes JD, McMahon M, Chowdhry S, Dinkova-Kostova AT (2010) Cancer chemoprevention mechanisms mediated through the keap1-nrf2 pathway
Sacks D, Baxter B, Campbell BC, Carpenter JS, Cognard C, Dippel D, Eesa M, Fischer U, Hausegger K, Hirsch JA (2018) Multisociety consensus quality improvement revised consensus statement for endovascular therapy of acute ischemic stroke
