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BDNF-induced long-term potentiation in the dentate gyrus in vivo is associated with phosphorylation of elongation factor-2

In mammalian cells, ER stress leads to an integrated stress response involving the related transmembrane kinases Ire1, Ire1 and PKRlike ER kinase (PERK), and the transmembrane activating transcription factor 6 (ATF6) (Zhang & Kaufman, 2004)

Cameron AD, Sinning I, LHermite G, Olin B, Board PG, Mannervik B, et al

Despite the high response rates and prolonged progression-free survival, relapses are still inevitable in a significant proportion of patients (Deng et al., 2024)
