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[DOI] [PubMed] [Google Scholar] 237.Hoofnagle J.H
When acetaminophen intake far exceeds therapeutic doses, the glucuronidation and sulfation path-ways are saturated, and the P450-dependent pathway becomes increasingly important
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However, rs34361428, located on the ADH cluster, was the top associated SNP and was a powerful expression quantitative trait loci (eQTL) for ADH1B , ADH1A, and both eQTL and splicing quantitative trait loci (sQTL) for ADH1C [119]
