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Since orexin neurons are involved in the facilitation and/or maintenance of arousal 2123 , we hypothesized that IGF-I may form part of a feedback loop between the periphery and the hypothalamus to control the circadian pattern of activity by modulating orexinergic function
Sox9 is expressed along the germinal and proliferating zones of the growth plate while its levels are naturally diminished in the hypertrophic zone
[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Sharma D et al
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