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Activation and nuclear translocation of the primary transcription factor Nrf2 promote the expression of these enzymes, providing robust protection against oxidative damage [44]

That is the core distinction

Katona PG et al (1977): Opposing central and peripheral effects of atropine on parasympathetic cardiac control

Ferroptosis inhibition is being explored across a wide range of disease areas, and the number of identified ferroptosis inhibitors has grown extensive [27, 122,123,124]
