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Quick answer: XenNAD+'s confirmed per-patch doses are modest - single-digit milligrams per ingredient

Dufour A, Lafont JE, Buffier M, Verset M, Cohendet A, Contamin H, et al

10.3390/ph12010026 66 KowdleyK

NAPQI is neurotoxic : Crosses the placenta, depletes fetal brain glutathione, generates oxidative stress, and triggers cell death in neural tissue at doses below those causing maternal liver toxicity
