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Of note, in the absence of activating stimuli, unstimulated T cells did not exhibit relevant expression levels of immune cytokines, irrespective of their nutritional situation (Appendix Fig S1C and D)
Notably, the WHI randomized trials (163, 168) and a meta-analysis (169) have demonstrated that treatment with CEE alone significantly decreases the risk of breast cancer
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Some preclinical work has also reported preserved or enhanced lean muscle for example, greater grip strength in aged mice when combined with exercise [7]
