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Our goal is to move beyond the hype and facilitate a critical evaluation of the current scientific landscape, empowering informed decision-making in practice

For women, this shift may unmask genetic susceptibility to androgenic alopecia that was previously masked by higher estrogen levels

In brief, lipidomics for each sample were performed by the Vanquish UPLC systems coupled to a Q Exactive HF (QE-HF) mass spectrometer equipped with HESI (Thermo Fisher Scientific, Waltham, MA)

Glutathione peroxidase 4 (GPX4) as a selenoperoxidase is a key upstream regulator of ferroptosis which plays two simultaneous roles, one in converting reduced GSH to glutathione disulfide (GSSG) and the other is to inhibit ferroptosis by reducing phospholipid hydroperoxides (PLOOHs) to the corresponding alcohols (PLOHs), thereby preventing the accumulation of lipid peroxides (Jiang et al., 2021)