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Wilson Tang, M.D., Zeneng Wang, Ph.D., Bruce S

Chronic administration of high doses of oral levocarnitine in patients with severely compromised renal function or in ESRD patients on dialysis may result in accumulation of the potentially toxic metabolites, trimethylamine and trimethylamine-N-oxide, since these metabolites are normally excreted in the urine

Subsequently, subjects who are supplemented with L-carnitine for two weeks had a reduction in lipid peroxidation (based on the thiobarbituric acid-reactive substance method) and muscle damage markers (malondialdehyde, creatine kinase, and lactate dehydrogenase) with a concurrent increase in total antioxidant capacity [16]

It is important to follow a varied and balanced diet and maintain a healthy lifestyle