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Vascular endothelial growth factor receptor KDR tyrosine kinase activity is increased by autophosphorylation of two activation loop tyrosine residues

10.1038/sj.jid.5700253 [DOI] [PubMed] [Google Scholar] Okabe S., Amagase K

A small needle or cannula is inserted into a vein, typically in the arm

The most common adverse events are gastrointestinal: nausea (occurring in 12-33% of subjects depending on dose), diarrhea, constipation, and decreased appetite
