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Fumaric acid esters Fumaric acid esters are the most investigated NRF2 activators
The relevance of these findings to human urinary bladder cancer is not clear, since at least one prospective cohort study found cruciferous vegetable consumption to be inversely associated with the risk of bladder cancer in men (71)
doi: 10.1038/s41591-019-0675-0
In the United States, CJC-1295 has been available through compounding pharmacies, though recent FDA actions have raised questions about its continued compounding availability
