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Why Are Tesamorelin, CJC-1295, and Ipamorelin Combined Together

doi: 10.2337/diab.45.1.91 [DOI] [PubMed] [Google Scholar] 228

The result is a synergistic GH secretion profile that neither compound achieves in isolation, combining GHRH-receptor-driven cAMP/PKA somatotroph amplification with GHS-R1a-mediated intracellular calcium mobilisation for a physiologically pulsatile, dual-pathway GH response

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