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It was originally developed as a potential treatment for obesity by researchers at Monash University

When combined with semaglutide (CagriSema), weight loss increases to 15-25%, making it one of the most powerful medical weight loss options available

The British National Formulary (BNF), for example, differentiates the prescription of hydroxocobalamin according to presenting symptoms, eg, For neurological involvement, it is advised to administer hydroxocobalamin by intramuscular injection, initially 1 mg once daily on alternate days until no further improvement, then 1 mg every 2 months. In the Netherlands, pharmacotherapeutic guidelines 51 recommend (for the same neurological symptoms or abnormalities) administration of 1000 mcg once or twice weekly for up to two years

Administration The iron infusion is usually administered in a healthcare setting, such as a hospital or clinic