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doi: 10.1016/j.abb.2005.10.019

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1 CFTR mutations are grouped into 6 functional classes based on the primary molecular defect

At the same time, OS can promote the proliferation of theca-interstitial cells, upregulate CYP17, reduce serum SHBG levels, increase androgen secretion, improve the biological activity of serum free testosterone, and cause HA
