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Pregnancy: Teratogenic Effects
Laminotomy removes only a portion of the lamina, carving a window just large enough to relieve pressure in one specific spot

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GLP-1 signaling and hepatic steatosis Human hepatocytes express little or no GLP-1 receptor, so most experts believe semaglutides liver benefits are largely indirect mediated by weight loss, reduced adipose lipolysis, improved insulin sensitivity, lower glucotoxicity, and decreased hepatic lipogenic drive rather than by direct receptor engagement on liver cells