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Oral Administration of Quercetin or its Derivatives Inhibit Bone Loss in Animal Model of Osteoporosis

Their mechanism in this context involves the downregulation of pro-inflammatory cytokines including interleukin-1 alpha and tumor necrosis factor that directly damage follicular epithelium and disrupt the dermal papilla's signaling function

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For an inclusion complex of stoichiometry 1:1 (D-CD complex, Equation (2) where k d(D) and k d(D-CD) are the observed rate constant for the decomposition of free drug and of the D-CD complex, respectively)