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Brain Function: L-Carnitine (specifically Acetyl-L-Carnitine) can cross the blood-brain barrier and may have neuroprotective and cognitive benefits

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Despite these mice also consumed a comparable amount of standard laboratory chow (62% carbohydrate) 94 as the Atm -WT mice on vehicle (Supplementary Fig

SASP-induced disruption of the microglial secretome results in the alteration of the homeostatic balance necessary for proper neuronal function, leading to an increase in molecules such as IL-6, IL-1, TNF-, an increase in inflammasome-related proteins and ROS, as well as increased expression of Nox2 by microglia (Ritzel et al., 2015