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Such variation in clinical presentation strongly indicates that, beyond protein stability and genetic factors, additional influences contribute to disease onset and progression
Acknowledgements We apologize to all the scientists whose work could not be discussed in the pages of this review
170 Treatment with TGF-1 inhibitor LY2157299 before inducing MCAO significantly reduced -catenin expression in a rat model
In the MMR-D cohort, 12-month PFS was 63.5%, compared to 24.4% in the placebo arm, and 24-month PFS was 61.4%, compared to 15.7% in the placebo arm, HR 0.28 (95% CI 0.160.50)
