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A study ( 3 H-PL-10.1.AK-15

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H 2 O 2 , a product of MnSOD activity, acts as a signaling molecule in energy metabolism and thermogenesis, modulating the uncoupling proteins by desensitizing them to inhibition and activating them through modifications like sulfenylation of UCP1-Cys253 and glutathionylation of UCP2-3 [40]

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