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Chemical conjugation of epothilone with glutathione is one of the most successful trials to overcome the technical hurdles of this compound [75], however, the complexity and toxicity of required cross-linking chemicals are the major challenge

A secondary anti-rabbit IgG HRP-conjugated antibody and anti-mouse IgG HRP-conjugated antibody were used

Such mechanistic insights provide a foundation for further exploration of prevention and therapeutic strategies aimed at mitigating risk factors and intervening in these pathogenic processes

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