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l-cysteine và glutathione Frontiers Cysteine, Glutathione, and Thiol Redox

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doi: 10.1038/nrrheum.2017.43 37 ZhangHWangLChuY

l-cysteine v glutathione Frontiers Cysteine, Glutathione, and Thiol Redox

The cells were fixed in 4% paraformaldehyde and washed three times with PBS

l-cysteine v glutathione Frontiers Cysteine, Glutathione, and Thiol Redox

Under control conditions, a 100 M tBuOOH exposure led to little or no cell damage (93 5% of cell survival, n = 12)

l-cysteine v glutathione Frontiers Cysteine, Glutathione, and Thiol Redox

Examining these datasets, we find that HCC patients with high serum AFP levels (Fig 4E) or high tissue AFP expression (HpSC subtype in Fig 4F) exhibit lower tumor GSH abundance than those with low serum or tissue AFP (correlation between GSH abundance and MYC expression in MH and HpSC subtypes in Fig EV5A and B)

l-cysteine v glutathione Frontiers Cysteine, Glutathione, and Thiol Redox

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