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When used in topical formulations, the most commonly reported issues are localised and mild, and may include: Skin irritation or redness at the site of application Contact dermatitis in individuals with sensitive skin or known peptide sensitivities Scalp itching or tingling , which may be transient The following precautions are advised: Avoid application to broken, inflamed, or irritated skin , and keep the product away from the eyes and mucous membranes

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therefore, redox homeostasis plays a pivotal role in protecting cancer cells against them

They found significant reduction of SOD activities and serum levels of zinc, copper and manganese in healthy pregnant women compared to non-pregnant women with further reduction in RM patients