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These present a continuous endothelium that is in intimate contact with the cardiomyocytes (only 1 m apart), allowing for direct cellular communication and signaling, and thus regulating their function [20, 34]

Injury location: Areas with better blood supply typically heal faster than poorly vascularized tissues

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Although lipohypertrophy usually doesnt spread, the lump can get bigger over time if you continue to inject medication in the same place
