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Orthostatic Intolerance and Tachycardia: In dysautonomia and POTS, poor vascular tone causes blood to pool in the lower extremities upon standing, forcing the heart to race to compensate
10.1002/jbt.23619 31 GuJ.ZhangP.LiH.WangY.HuangY.FanL.et al (2024)
Survival or death of neural cells in the penumbra correlates with the frequency of these transient ischaemic depolarisations
In addition, ROS modifies the intracellular influx of calcium, resulting in interstitial oedema, haemoconcentration, and ischemia, as well as further production of ROS, creating a self-perpetuating cycle [47]
