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CRISPRa employ dCas9 fused to transcriptional activators to upregulate gene expression, while CRISPRi use dCas9-repressor fusions to silence gene transcription, facilitating functional genomics studies and potential therapeutic gene modulation (68, 69)
LC reduces the death rate of nerve cells and the damage associated with aging [88], thanks to its cholinomimetic activity [89]
Association of diabetes mellitus with risk of reproductive impairment in females: a comprehensive review
