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[83] demonstrated that fisetin significantly reduced senescent cell burden in murine chondrocytes (ATDC5) and pre-osteoblasts (MC3T3) in vitro, while Zhao et al
We dissect each clathrin box by mutagenesis to track their occupancy by the Ent1 and Ent2 adaptors and show that both Ent1 and Ent2 exhibit different Chc binding patterns, as revealed by native MS and photobleaching FRET assays
However, since only a few synthetic ATs have been approved for medicinal use thus far, it seems that their success in medicine is disappointing
PMID: 61 BergVModakMBrellJPuckAKnigSJutzSet al
