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By inhibiting NNMT, 5-Amino-1MQ has been shown to increase intracellular NAD+ and SAM availability, upregulate polyamine flux enzymes, and alter histone methylation patterns in preclinical adipocyte models
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1,2,6 The resultant abnormal erythropoiesis can trigger other notable abnormal laboratory findings, such as decreased haptoglobin levels, high lactate dehydrogenase levels, and elevated reticulocyte count
