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These survival benefits have been recapitulated in a Caenorhabditis elegans model of Menkes disease (Yuan et al., 2022)

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High-density lipoprotein cholesterol (HDL-C) typically reaches its highest concentrations during the late follicular or periovulatory phase, near the E2 surge, though this peak may be missed in studies comparing only broad follicular versus luteal averages [124,125]

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