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doi:10.1007/s00253-001-0902-7

"B-Vitamins and Bone HealthA Review of the Current Evidence"

In summary, the key interactions to consider are pyridoxines reduction of levodopa and anticonvulsant efficacy, niacinamides additive effects on blood pressure, blood sugar, and gout management, and the potential need for B-vitamin repletion in patients on certain medications (diuretics, isoniazid, etc.)

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