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It is assumed that the absence of an organic anion transporter from these cells could explain this finding, since it has been established that haloalkene conjugates enter cells via the basolaterally located anion transporters (Lock et al., 1986)

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Histological examination of CTE patients with repeated trauma has revealed focal perivascular accumulation of hyperphosphorylated tau as NFTs within neurons, neuropil threads and astrocytic tangles, with a heightened propensity within the depths of cortical sulci