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The carriers of CYP3A5 rs776746 A allele were overrepresented in the intentionally overdosed group and were more predisposed to acetaminophen-induced hepatotoxicity than individuals with the G allele, that rendered CYP3A5 enzyme inactive due to aberrant gene splicing [100]
2022 [Google Scholar] 171.Evers M.J.W., van de Wakker S.I., de Groot E.M., de Jong O.G., Gitz-Franois J.J.J., Seinen C.S., Sluijter J.P.G., Schiffelers R.M., Vader P
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Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells
