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However, even if the absolute variation in cell size (standard deviation or RDW-SD) hasnt changed, once the average size (MCV) becomes much smaller (i.e., microcytosis), the same absolute variation might become more biologically meaningful or, put another way, relatively larger compared to the new, smaller mean

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Figure 3 Figure 4 Lactate transport directionality changes in the aging metabolic system One of the central fueling mechanisms in brain neuroenergetics is the astrocyte-to-neuron lactate shuttle (ANLS)