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Rabbits indeed appear to be a better model than mice for the study of atherosclerotic effects of apoC1, because (1) rabbits fed with cholesterol-rich diet spontaneously develop atherosclerotic lesions, as humans but not as mice [143] (2) plasma lipid profile of rabbits is closer to humans than the one of mice and (3) rabbits, like humans, express endogenous, active CETP [144]

Huang, L