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Preparation of microsome Microsome was prepared as described previously 42

Hence, therapeutic agents targeting oxidative stress, apoptosis, and inflammation may be beneficial in clinical approach to RIRI

Jevtic G, Nikolic T, Mircic A, Stojkovic T, Velimirovic M, Trajkovic V, Markovic I, Trbovich AM, Radonjic NV, Petronijevic ND (2016) Mitochondrial impairment, apoptosis and autophagy in a rat brain as immediate and long-term effects of perinatal phencyclidine treatment - influence of restraint stress

Although iRPE cells derived from pluripotent stem cells do not recapitulate the complex microenvironment of the outer retina, they provide a suitable model for studying AMD mechanisms