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A short treatment period (3 days) with either NAC or L-acetylcarnitine, but not fluoxetine, corrected the depressive-like phenotype in these mice by inducing resilience to stress [139]
This suggests that immune dysregulation-induced gut microbiota dysbiosis and activation of the kynurenine pathway cause acute tryptophan depletion in the gut
Sanger, Queen Mary University of London, United Kingdom Updates Copyright 2020 Van den Houte, Scarpellini, Verbeure, Mori, Schol, Masuy, Carbone and Tack
