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Description
It has been shown that in patients with type 2 diabetes mellitus (T2DM) the response to the incretin effect is altered as a result of a severe defect in the sensitivity for GIP in the cells [4] and a reduction in food-induced GLP-1 secretion [5, 6]

Individual contracted rates vary
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[94] reported that HFD-feeding increased the production of endotoxin LPS by gram-negative bacteria in the intestinal microbiota of mice
