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In addition to acting on opioid receptors, opioid peptides have also been shown to interact with toll-like receptors (TLR), particularly TLR4 (Eidson and Murphy 2013
BPC 157, or Body Protective Compound 157, is a peptide derived from a naturally occurring protein in the human body
In the Billon 2023 paper, mice given 30 mg/kg IP still showed measurable plasma and muscle concentrations at 6 hours post-injection, which helps explain why twice-daily dosing was used in efficacy studies
