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As is mentioned above, CPTIC overexpression in cancer cells promotes FAO and resistance to mTORC1 inhibitors
Notably, TMAO can induce various types of cell death, including necrosis and programmed cell death (PCD)
Mitochondria-Associated Membranes Response to Nutrient Availability and Role in Metabolic Diseases
This shift in understanding began with the seminal study by Wang et al
