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It was found that CXB-NE, in turn, affected the regulation and expression of genes in sciatic nerve induced by CCI through targeted inhibiting macrophage COX2 and lowering macrophage PGE2, which was characterized by decreased expression of several neuroinflammatory genes (150, 151)

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K., Ryals, J

All of these proposed explanations are unsatisfying, with a combination of weak evidence and low prior probabilities
