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In conclusion, these results show that patients having tumors with high CA IX expression have higher risk of disease progression, and development of metastases, independent of tumor type or site

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The cause of endolymphatic hydrops is unclear, and while all patients with Mnire disease have endolymphatic hydrops, not all patients with endolymphatic hydrops have Mnire disease, which has led to the suggestion of an array of possible causes including genetic predisposition, viral infection, and multiple other biochemical and immune factors