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Evaluation of SMN Protein, Transcript, and Copy Number in the Biomarkers for Spinal Muscular Atrophy (BforSMA) Clinical Study

Studies on pharmacokinetics [25] and renal clearance of TMAO [26] in healthy human subjects suggest that TMAO has a small volume of distributionabout one half that of ureabut a higher renal clearance compared to urea and creatinine

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Mol Cell Proteomics 19(7):1104-19 2020 PMC7338085 Martin-Perez M, Grillo AS, Ito TK, Valente AS, Han J, Entwisle SW, Huang HZ, Kim D, Yajima M, Kaeberlein M, Villen J