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In plants, there are two key enzymes involved in AsA recycling known as dehydroascorbate reductase (DHAR) and monodehydroascorbate reductase (MDHAR)

Mechanistic enzymology in drug discovery: a fresh perspective

In addition, rapid mucociliary clearance renews the mucus layer roughly every 1020 min, limiting residence time and absorption (Chung et al., 2023

Large doses of vitamin B 6 (pyridoxine) should be avoided to prevent the peripheral conversion of levodopa (L-dopa) to dopamine, which interferes with the efficacy of L-dopa therapy
