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The safety data
Intriguingly, approximately half of the MCT4-downregulated animals also lost their BOLD response, and this deficit could be rescued by peripheral lactate infusion, a rescue not possible in MCT2-downregulated rats

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10.1016/j.cub.2005.09.014 [DOI] [PubMed] [Google Scholar] Dupre-Crochet S., Erard M., Ne O
