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Notably, supplementing NADPH and using a pharmacological inhibitor of aldose reductase an enzyme using NADPH oxidase for the formation of sorbitol in high-glucose conditions - successfully restored the sensitivity to LPS-induced NET formation in high glucose conditions, while reducing high glucose-induced cytosolic ROS production, neutrophil elastase secretion and spontaneous NET release (Joshi et al., 2020) (Table 4)
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We mainly summarize the most recent research progress in the field of ASD oxidative stress biomarkers in this review
2024;31:e12837
