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In 2021, it resulted in a mean weight loss of roughly 15% and maintenance through decreased appetite

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Ajit Bolar, N

It is assumed that dsRNA editing by ADAR could result in weakened recognition by the helicase domain of Dicer-2 which functions as a cytosolic sensor for dsRNA to trigger immune signalling, independent of dicer enzymatic activity (137) (see section 7.3)
